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A 1.375-Approximation Algorithm for Sorting by Transpositions with Faster Running Time

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Advances in Bioinformatics and Computational Biology (BSB 2022)

Abstract

Sorting Permutations by Transpositions is a famous problem in the Computational Biology field. This problem is NP-Hard, and the best approximation algorithm, proposed by Elias and Hartman in 2006, has an approximation factor of 1.375. Since then, several researchers have proposed modifications to this algorithm to reduce the time complexity. More recently, researchers showed that the algorithm proposed by Elias and Hartman might need one more operation above the approximation ratio and presented a new 1.375-approximation algorithm using an algebraic approach that corrected this issue. This algorithm runs in \(O(n^6)\) time. In this paper, we present an efficient way to fix Elias and Hartman algorithm that runs in \(O(n^5)\). By comparing the three approximation algorithms with all permutations of size \(n \le 12\), we also show that our algorithm finds the exact distance in more instances than the previous two algorithms.

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Acknowledgment

This work was supported by the National Council of Technological and Scientific Development, CNPq (grants 140272/2020-8, 202292/2020-7, and 425340/2016-3), the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001, and the São Paulo Research Foundation, FAPESP (grants 2013/08293-7, 2015/11937-9, and 2019/27331-3).

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Correspondence to Alexsandro Oliveira Alexandrino .

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Alexandrino, A.O., Brito, K.L., Oliveira, A.R., Dias, U., Dias, Z. (2022). A 1.375-Approximation Algorithm for Sorting by Transpositions with Faster Running Time. In: Scherer, N.M., de Melo-Minardi, R.C. (eds) Advances in Bioinformatics and Computational Biology. BSB 2022. Lecture Notes in Computer Science(), vol 13523. Springer, Cham. https://doi.org/10.1007/978-3-031-21175-1_16

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  • DOI: https://doi.org/10.1007/978-3-031-21175-1_16

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