Study of the evolution of antiemetic treatment through the application of Triadic Formal Concept Analysis
Cancer treatment is always improving with new techniques and drugs, applied in a process with rigorous medical analysis. One way to analyze medical outcomes is to test a new drug in one group and placebos in another. In this article, we used a database with the results of a new drug for preventing chemotherapy-induced nausea and vomiting. After processing the database, we apply the Triadic Formal Concept approach to extract triadic rules, implications, and conditions that are used to identify correlations throughout the medical sessions. Our study shows that triadic analysis can help scientists perform clinical analyzes efficiently by looking at patient history data.
Ganter, B. and Obiedkov, S. Conceptual exploration, 2016.
Ganter, B. and Wille, R. Formal concept analysis, 1999.
Hu, B., Dasmahapatra, S., Dupplaw, D., Lewis, P., and Shadbolt, N. Managing patient record instances using dlenabled formal concept analysis. Engineering Knowledge in the Age of the Semantic Web Lecture Notes in Computer Science, 2004.
Missaoui, R. and Emamirad, K. Lattice miner-a formal concept analysis tool. 14th International Conference on Formal Concept Analysis, 2017.
Navari, R. M., Qin, R., Ruddy, K. J., Liu, H., Powell, S. F., Bajaj, M., Dietrich, L., Biggs, D., Lafky,
J. M., Loprinzi, C. L., and et al. Olanzapine for the prevention of chemotherapy-induced nausea and vomiting. New England Journal of Medicine 375 (2): 134–142, 2016.
Ng, T. L., Hutton, B., and Clemons, M. Chemotherapy-induced nausea and vomiting: Time for more emphasis on nausea? The Oncologist 20 (6): 576–583, 2015.
Singh, P. K., Kumar, C. A., and Gani, A. A comprehensive survey on formal concept analysis, its research trends and applications. International Journal of Applied Mathematics and Computer Science 26 (2): 495–516, 2016.
Wille, R. Why can concept lattices support knowledge discovery in databases? Journal of Experimental & Theoretical Artificial Intelligence 14 (2-3): 81–92, 2002.
Yeo, W., Chan, V. T., Li, L., Lau, T. K., Lai, K. T., Pang, E., Cheung, M., and Mo, F. K. Dataset on chemotherapy-induced nausea and vomiting (cinv) and quality of life (qol) during multiple chemotherapy cycles among a chinese breast cancer patient population who were randomized to antiemetic regimens with or without olanzapine. Data in Brief vol. 30, pp. 105421, 2020.
Zhuk, R., Ignatov, D. I., and Konstantinova, N. Concept learning from triadic data. Procedia Computer Science vol. 31, pp. 928–938, 2014.