Biophysical Chemistry of Macromolecules Research Group at the State University of Maringá
DOI:
https://doi.org/10.5753/jidm.2024.2607Keywords:
Bioinformatics, Machine learning, Molecular docking, Molecular dynamics, Virtual screeningAbstract
The interdisciplinary field of Biophysical Chemistry, which applies concepts from Physical Chemistry to describe biological phenomena, is essential for modern molecular biology advancements. This approach enables the description of biological systems in terms of their constituent parts, such as atoms and molecules, facilitating a structural understanding of their characteristics. Nonetheless, to describe such large systems, computational methods are needed. The Biophysical Chemistry of Macromolecules research group at the State University of Maringá is dedicated to investigating such systems, mainly protein-ligand complexes, through bioinformatics approaches combined with experimental techniques to validate in silico results. The main purpose of the research projects is to develop applications for drug discovery in the context of antimicrobial, antiviral, antifungal, and antihyperglycemic agents, with the aim of advancing the field of bioinformatics in Brazil.
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