Simulation of Scale Free Gene Regulatory Networks based on Threshold Functions on GPU

  • Raphael R. Campos UFV
  • Ricardo Ferreira UFV
  • Julio C. Goldner Vendramini UFV
  • Fábio Cerqueira UFV
  • Marcelo Lobato Martins UFV

Resumo


Gene regulatory networks have been used to study diseases and cell evolution, where Random Boolean graphs are one of computational approaches. A Boolean graph is a simple and effective model, and its dynamic behavior has been used in several works. This article proposes an efficient environment to simulate Boolean graph on GPU (Graphics Processing Units). The dynamic behavior of a Boolean graph is computed by visiting the whole or a subset of state space. The proposed tool is based on statistical approaches to evaluate large graphs. Moreover, it can take into account scale free graphs with threshold functions. The experimental results show a speed-up factor of up to 40 times. In addition, the exploration of state spaces three orders of magnitude greater than previous approaches have been evaluated.

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Publicado
26/10/2011
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CAMPOS, Raphael R.; FERREIRA, Ricardo; VENDRAMINI, Julio C. Goldner; CERQUEIRA, Fábio; MARTINS, Marcelo Lobato. Simulation of Scale Free Gene Regulatory Networks based on Threshold Functions on GPU. In: SIMPÓSIO EM SISTEMAS COMPUTACIONAIS DE ALTO DESEMPENHO (SSCAD), 12. , 2011, Vitória. Anais [...]. Porto Alegre: Sociedade Brasileira de Computação, 2011 . p. 81-88. DOI: https://doi.org/10.5753/wscad.2011.17271.