Parkinson sEMG signal prediction and generation with Neural Networks
ResumoParkinson’s Disease (PD) is a neurodegenerative disorder characterized by symptoms like resting and action tremors, which cause severe impairments to the patient’s life. Recently, many assistance techniques have been proposed to minimize the disease’s impact on patients’ life. However, most of these methods depend on data from PD’s surface electromyography (sEMG), which is scarce. In this work, we propose the first methods, based on Neural Networks, for predicting, generating, and transferring the style of patient-specific PD sEMG tremor signals. This dissertation contributes to the area by i) comparing different NN models for predicting PD sEMG signals to anticipate resting tremor patterns ii) proposing the first approach based on Deep Convolutional Generative Adversarial Networks (DCGANs) to generate PD’s sEMG tremor signals; iii) applying Style Transfer (ST) for augmenting PD’s sEMG signals with publicly available datasets of non-PD subjects; iv) proposing metrics for evaluating the PD’s signal characterization in sEMG signals. These new data created by our methods could validate treatment approaches on different movement scenarios, contributing to the development of new techniques for tremor suppression in patients.
Bo, A. P. L. (2010). Compensation active de tremblements pathologiques des membres supérieurs via la stimulation électrique fonctionnelle. PhD thesis, Montpellier II.
Delaney, A. M., Brophy, E., and Ward, T. E. (2019). Synthesis of realistic ecg using generative adversarial networks. ArXiv, abs/1909.09150
Gatys, L. A., Ecker, A. S., and Bethge, M. (2015). A neural algorithm of artistic style. ArXiv, abs/1508.06576.
Guerrero, A. and Mac´ıas-D´ıaz, J. E. (2019). A package for the computational analysis of complex biophysical signals. International Journal of Modern Physics C, 30(01)
Johnson, J., Alahi, A., and Fei-Fei, L. (2016). Perceptual losses for real-time style transfer and super-resolution. In ECCV.
Organization., W. H. (2006). Neurological disorders: public health challenges.
Petersen, E. and Rostalski, P. (2019). A comprehensive mathematical model of motor unit pool organization, surface electromyography, and force generation. Frontiers in Physiology, 10:176.
Philipson, B. J. (2009). System and methods for emg-triggered neuromuscular electrical stimulation. US 2009/0171417A1.
Semmlow, J. L. and Griffel, B. (2014). Biosignal and Medical Image Processing. CRC.
Zanini, R. A. and Colombini, E. L. (2020). Parkinson’s disease emg data augmentation and simulation with dcgans and style transfer. Sensors, 20(9).
Zanini, R. A., Colombini, E. L., and de Castro, M. C. F. (2019). Parkinson’s disease emg signal prediction using neural networks. In 2019 IEEE International Conference on Systems, Man and Cybernetics (SMC), pages 2446–2453.