Detailed reconstruction for coronary arteries integrating angiographies and IVUS studies

• G. D. Maso Talou LNCC / INCT-MACC
• P. J. Blanco LNCC / INCT-MACC
• I. Larrabide CONICET
• C. Guedes Bezerra USP
• P. A. Lemos USP
• R. A. Feijóo LNCC / INCT-MACC

Resumo

The early prediction and/or detection of cardiovascular diseases are of paramount importance worldwide due to the increasing mortality and morbidity rate in the global population. Specifically, key factors for its assessment such as atherosclerotic plaque evolution and vulnerability in coronary arteries are still poorly understood, although in the last decade emerging techniques based on computational models provided a complementary approach towards these problems. To apply these models to patient specific scenarios, a geometric representation of the patient coronary vessels must be accurately constructed in three dimensional space. To achieve this purpose, we present a reconstruction methodology that aims to integrate the high definition provided by intravascular ultrasound about the vessel structure, with the spatial information presented in orthogonal angiographies. As result, the three-dimensional geometric reconstruction of the vessel at different cardiac phases along the cardiac cycle can be obtained, enabling the subsequent development of patient-specific computational models.

Referências

Cañero, C., Radeva, P., Toledo, R., Villanueva, J. J., and Mauri, J. (2000). 3d curve reconstruction by biplane snakes. In Proc. IEEE of ICPR, pages 563–566.

Carlier, S. G., van Damme, L. C. a., Blommerde, C. P., Wentzel, J. J., van Langehove, G., Verheye, S., Kockx, M. M., Knaapen, M. W. M., Cheng, C., Gijsen, F., Duncker, D. J., Stergiopulos, N., Slager, C. J., Serruys, P. W., and Krams, R. (2003). Augmentation of wall shear stress inhibits neointimal hyperplasia after stent implantation: inhibition through reduction of inflammation? Circulation, 107(21):2741–6.

Caro, C. G. (2009). Discovery of the role of wall shear in atherosclerosis. Arterioscler., Thromb., Vasc. Biol., 29(2):158–61.

Chatzizisis, Y. S., Jonas, M., Coskun, A. U., Beigel, R., Stone, B. V., Maynard, C., Gerrity, R. G., Daley, W., Rogers, C., Edelman, E. R., Feldman, C. L., and Stone, P. H. (2008). Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history study. Circulation, 117(8):993–1002.

Feldman, C. L., Ilegbusi, O. J., Hu, Z., Nesto, R., Waxman, S., and Stone, P. H. (2002). Determination of in vivo velocity and endothelial shear stress patterns with phasic flow in human coronary arteries: A methodology to predict progression of coronary atherosclerosis. Am Heart J, 143(6):931–939.

Finn, S., Glavin, M., and Jones, E. (2011). Echocardiographic speckle reduction comparison. Ultrasonics, Ferroelectrics and Frequency Control, IEEE Transactions on, 58(1):82 –101.

Giannoglou, G. D., Chatzizisis, Y. S., Sianos, G., Tsikaderis, D., Matakos, A., Koutkias, V., Diamantopoulos, P., Maglaveras, N., Parcharidis, G. E., and Louridas, G. E. (2006). In-vivo validation of spatially correct three-dimensional reconstruction of human coronary arteries by integrating intravascular ultrasound and biplane angiography. Coronary Artery Dis, 17(6):533–543.

Honda, Y. and Fitzgerald, P. J. (2008). Frontiers in intravascular imaging technologies. Circulation, 117(15):2024–37.

Kass, M., Witkin, A., and Terzopoulos, D. (1988). Snakes: active contour models. Int J Comput Vision, pages 321–331.

Krissian, K., Westin, C., Kikinis, R., and Vosburgh, K. (2007). Oriented speckle reducing anisotropic diffusion. IEEE Trans. Image Processing, 16(5):1412–1424.

Maso Talou, G. D. (2013). Ivus images segmentation driven by active contours and spacio-temporal reconstruction of the coronary vessels aided by angiographies. Master’s thesis (in portuguese), National Laboratory for Scientific Computing.

Maso Talou, G. D., Larrabide, I., Lemos, P. A., Blanco, P. J., and Feijóo, R. A. (2014). Decomposition of ivus studies in cardiac phases. In Proceedings of the 1st Biomedical Signal Analysis Conference (Florianópolis, March 25-28).

Michailovich, O. and Tannenbaum, A. (2006). Despeckling of medical ultrasound images. IEEE Trans. Ultrason Ferroelectrics Freq Contr, 53(1):64 –78.

Naghavi, M., Libby, P., Falk, E., et al. (2003). From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies. Circulation, 108(15):1772–8.

Slager, C. J., Wentzel, J. J., Schuurbiers, J. C. H., Oomen, J. A. F., Kloet, J., Krams, R., von Birgelen, C., van der Giessen, W. J., Serruys, P. W., and de Feyter, P. J. (2000). True 3-dimensional reconstruction of coronary arteries in patients by fusion of angiography and ivus (angus) and its quantitative validation. Circulation, 102:511–516.

Stone, P. H., Coskun, A. U., Kinlay, S., Clark, M. E., Sonka, M., Wahle, A., Ilegbusi, O. J., Yeghiazarians, Y., Popma, J. J., Orav, J., Kuntz, R. E., and Feldman, C. L. (2003). Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study. Circulation, 108(4):438–44.

Wentzel, J. J., Janssen, E., Vos, J., Schuurbiers, J. C. H., Krams, R., Serruys, P. W., de Feyter, P. J., and Slager, C. J. (2003). Extension of increased atherosclerotic wall thickness into high shear stress regions is associated with loss of compensatory remodeling. Circulation, 108(1):17–23.

Wentzel, J. J., Kloet, J., Andhyiswara, I., Oomen, J. a. F., Schuurbiers, J. C. H., de Smet, B. J. G. L., Post, M. J., de Kleijn, D., Pasterkamp, G., Borst, C., Slager, C. J., and Krams, R. (2001). Shear-Stress and Wall-Stress Regulation of Vascular Remodeling After Balloon Angioplasty : Effect of Matrix Metalloproteinase Inhibition. Circulation, 104(1):91–96.

Winter, S. A. D., Hamers, R., Degertekin, M., Tanabe, K., Lemos, P. A., Serruys, P. W., and Roelandt, J. (2003). A Novel Retrospective Gating Method for Intracoronary Ultrasound Images based on Image Properties. pages 13–16.

Xu, C. and Prince, J. L. (1998). Snakes, shapes, and gradient vector flow. IEEE Trans. on Image Processing, 7(3):359–369.