Utilizing Ontocancer to trace the profile of genomic stability maintenance pathways

• Rafael T. Pereira UFSM
• Renato P. de Azevedo UFSM
• Eder M. Simão UFSM
• José C. M. Mombach UFSM
• Giovani R. Librelotto UFSM

Abstract

The Ontocancro project provides a repository of cancer related information where researchers can find interactome and transcriptome data related to the metabolic pathways of the genome maintaining mechanisms from several distinct databases. In this paper not only we describe Ontocancro but we also present an approach to characterise the profile of the metabolic pathways based on the Shannon’s Entropy. Such parameter provides a quantitative measure of the activity and diversity from the metabolic pathways.

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